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  <xs:element id="leu_AdvancesFromCustomersChange" abstract="false" name="AdvancesFromCustomersChange" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ProvisionForLossOnContractChange" abstract="false" name="ProvisionForLossOnContractChange" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_CostObligatedToDOE" abstract="false" name="CostObligatedToDOE" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ContractPhaseAxis" abstract="true" name="ContractPhaseAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="leu_InventoryLoansCurrent" abstract="false" name="InventoryLoansCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_UF6UnitsBorrowedInPeriodValue" abstract="false" name="UF6UnitsBorrowedInPeriodValue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_CustomerAMember" abstract="true" name="CustomerAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_Phase2Member" abstract="true" name="Phase2Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_TotalAmountProgramCost" abstract="false" name="TotalAmountProgramCost" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_CashCashEquivalentsandRestrictedCashAbstract" abstract="true" name="CashCashEquivalentsandRestrictedCashAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="leu_SharesWithheldForEmployeeTaxesMember" abstract="true" name="SharesWithheldForEmployeeTaxesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_SeparativeWorkUnitsOwedToCustomersAndSuppliers" abstract="false" name="SeparativeWorkUnitsOwedToCustomersAndSuppliers" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_BorrowedInventoryValuationChangeInPeriod" abstract="false" name="BorrowedInventoryValuationChangeInPeriod" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_UraniumMember" abstract="true" name="UraniumMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_DefinedBenefitPlanPensionPlanObligationTransferred" abstract="false" name="DefinedBenefitPlanPensionPlanObligationTransferred" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_IncreaseDecreaseInInventoriesOwedToSuppliers" abstract="false" name="IncreaseDecreaseInInventoriesOwedToSuppliers" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_InventoriesOwedToCustomersAndSuppliers" abstract="false" name="InventoriesOwedToCustomersAndSuppliers" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_PortionOfDefinedBenefitPlanBenefitObligationRelatedToRemeasurement" abstract="false" name="PortionOfDefinedBenefitPlanBenefitObligationRelatedToRemeasurement" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ExchangeOfPreferredStockForCommonStockAndCommonStockWarrant" abstract="false" name="ExchangeOfPreferredStockForCommonStockAndCommonStockWarrant" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_DefinedBenefitPlanPlanAssetsTransferred" abstract="false" name="DefinedBenefitPlanPlanAssetsTransferred" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ShortTermInventoryLoans" abstract="false" name="ShortTermInventoryLoans" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_DeferredRevenueAndAdvancesFromCustomersCurrentAndNoncurrent" abstract="false" name="DeferredRevenueAndAdvancesFromCustomersCurrentAndNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ProvisionForLossOnContractsUtilized" abstract="false" name="ProvisionForLossOnContractsUtilized" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ContractServicesSegmentMember" abstract="true" name="ContractServicesSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_CommonStockIssuanceProceedsInAccountsReceivableDomain" abstract="true" name="CommonStockIssuanceProceedsInAccountsReceivableDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_LowEnrichedUraniumSegmentMember" abstract="true" name="LowEnrichedUraniumSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_ConsolidatedBalanceSheetAbstract" abstract="true" name="ConsolidatedBalanceSheetAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="leu_WorkerscompensationfinancialassuranceMember" abstract="true" name="WorkerscompensationfinancialassuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_CustomerCMember" abstract="true" name="CustomerCMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_SeparativeWorkUnitsInventory" abstract="false" name="SeparativeWorkUnitsInventory" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_OtherForeignMember" abstract="true" name="OtherForeignMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_HALEUOpsContractMember" abstract="true" name="HALEUOpsContractMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_EquityRelatedCompensation" abstract="false" name="EquityRelatedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_OtherReconcilingAdjustmentsNet" abstract="false" name="OtherReconcilingAdjustmentsNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_GovernmentCostSharePercentage" abstract="false" name="GovernmentCostSharePercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="leu_CollateralForInventoryLoanMember" abstract="true" name="CollateralForInventoryLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_DirectCostsOfStockIssuance" abstract="false" name="DirectCostsOfStockIssuance" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_CustomerBMember" abstract="true" name="CustomerBMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_StockIssuedDuringPeriodValueNet" abstract="false" name="StockIssuedDuringPeriodValueNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_SWUSegmentMember" abstract="true" name="SWUSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="leu_Governmentcostshareportion" abstract="false" name="Governmentcostshareportion" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_HALEUDemoContractMember" abstract="true" name="HALEUDemoContractMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_InventoryLoansCurrentNoncurrent" abstract="false" name="InventoryLoansCurrentNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_AdditionalCostsObligatedToDOE" abstract="false" name="AdditionalCostsObligatedToDOE" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_PurchasePriceIncreasePerShare" abstract="false" name="PurchasePriceIncreasePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="leu_NewAmountProgramCost" abstract="false" name="NewAmountProgramCost" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_PropertyPlantAndEquipmentIncludedInAccountsPayableAndAccruedLiabilitiesMember" abstract="true" name="PropertyPlantAndEquipmentIncludedInAccountsPayableAndAccruedLiabilitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_StockIssuedDuringPeriodValueGross" abstract="false" name="StockIssuedDuringPeriodValueGross" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_IncreaseDecreaseinDeferredRevenueNetofDeferredCosts" abstract="false" name="IncreaseDecreaseinDeferredRevenueNetofDeferredCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ReclassificationOfStockBasedCompensationLiabilityToEquityMember" abstract="true" name="ReclassificationOfStockBasedCompensationLiabilityToEquityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_ContractValue" abstract="false" name="ContractValue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_SeparativeWorkUnitsNetOfLiability" abstract="false" name="SeparativeWorkUnitsNetOfLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_AdjustmentToRightOfUseLeaseDueToModificationDomain" abstract="true" name="AdjustmentToRightOfUseLeaseDueToModificationDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_UraniumInventory" abstract="false" name="UraniumInventory" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_CustomerDMember" abstract="true" name="CustomerDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_SeparativeWorkUnitsMember" abstract="true" name="SeparativeWorkUnitsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_LEUSegmentMember" abstract="true" name="LEUSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="leu_InventoryNetOfLiability" abstract="false" name="InventoryNetOfLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_UraniumInventoryNetOfLiability" abstract="false" name="UraniumInventoryNetOfLiability" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ReclassificationOfStockBasedCompensationLiabilityToEquity" abstract="false" name="ReclassificationOfStockBasedCompensationLiabilityToEquity" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_AccruedLoss" abstract="false" name="AccruedLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ScheduleofIntangibleAssetsandExcessReorganizationValueTableTextBlock" abstract="false" name="ScheduleofIntangibleAssetsandExcessReorganizationValueTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="leu_ContractWithCustomerAdvancesLiabilityCurrent" abstract="false" name="ContractWithCustomerAdvancesLiabilityCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_AwardsUnderExecutiveIncentivePlanPeriod" abstract="false" name="AwardsUnderExecutiveIncentivePlanPeriod" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="leu_TechnicalSolutionsSegmentMember" abstract="true" name="TechnicalSolutionsSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="leu_UraniumOwedToCustomersAndSuppliers" abstract="false" name="UraniumOwedToCustomersAndSuppliers" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_OtherfinancialassuranceMember" abstract="true" name="OtherfinancialassuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_CompanyCostSharePortion" abstract="false" name="CompanyCostSharePortion" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_IncreasedecreaseinAdvancesfromcustomersnoncurrent" abstract="false" name="IncreasedecreaseinAdvancesfromcustomersnoncurrent" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_EquityIssuanceCostsIncludedInAccountsPayableAndAccruedLiabilitiesMember" abstract="true" name="EquityIssuanceCostsIncludedInAccountsPayableAndAccruedLiabilitiesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_AccountsPayableUnderPurchaseAgreements" abstract="false" name="AccountsPayableUnderPurchaseAgreements" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="leu_ContractPhaseDomain" abstract="true" name="ContractPhaseDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_Phase1Member" abstract="true" name="Phase1Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="leu_RevaluationOfInventoryBorrowing" abstract="false" name="RevaluationOfInventoryBorrowing" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
